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in patients with congestive heart failure (CHF).3-5 Its mechanism of action is exerted through the inhibition of the enzyme carbonic an-hydrase, leading to a substantial increase in bicarbonate sodium and potassium renal excretion. 3,4 Its action is mainly localized in proximal tubule leading to an increased sodium concentration on more dis-

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An enzyme attracts substrates to its active site, catalyzes the chemical reaction by wh Background and Purpose We attempted to clarify the role of the acetazolamide-reactive mechanism in cerebral hemodynamic autoregulation and to establish a useful method of estimation using the acetazolamide test..
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Acetazolamide works by blocking the action of an enzyme called carbonic anhydrase. Blocking this enzyme reduces the amount of fluid (called aqueous humour) that you make in the front part of your eye, and this helps to lower the pressure within your eye. Acetazolamide is sometimes prescribed for other conditions which are not covered by this leaflet.

2020-10-23 · Aripirazole has a unique mechanism of action. It is a dopamine partial agonist at D2 receptors with efficacy in schizophrenia and a favourable side effect profile. This mechanism does not refute arguments that its primary site of action may still be inhibition of PG synthesis.